Sander Granneman

This study shows KhpA and KhpB in Campylobacter jejuni depend on each other for RNA recognition, with KhpA using a KH domain and KhpB an atypical R3H domain.

This study identifies PBP2a as an RNA-binding protein in MRSA, showing it interacts with hundreds of transcripts and its RNA-binding activity is crucial for oxacillin resistance.

This paper identifies RsaE, a non-coding RNA, as a regulator of psm transcript stability and biofilm properties in MRSA, showing its role in toxin expression, biofilm maturation, and dissemination.

This paper introduces an ABA-based anchor-away system for reversible nuclear protein depletion in yeast, overcoming limitations of the rapamycin-based system.

This study identifies RNMT's direct interaction with RNA G-quadruplexes, revealing a mechanism for gene-specific cap methylation during RNA processing.

This study investigates how NF45-NF90 heterodimers bind and coat long dsRNA, revealing structural changes and implications for RNA processing.

The paper shows that the NNS complex regulates RNA homeostasis in yeast by controlling the expression of the mitochondrial transporter Pic2, with defects causing growth defects and stress.

This study investigates how Sfp1 regulates mRNA synthesis and stability by interacting with Pol II and influencing mRNA fate through co-transcriptional binding.

pyRBDome enhances and interprets RNA-binding proteome data by integrating machine learning predictions and structural data to improve RBS detection and reduce false positives.

The paper shows Hfq regulates RecB protein levels in E. coli by reducing translation of recB mRNA, maintaining optimal RecB abundance.

This paper introduces diffBUM-HMM, a statistical model for detecting RNA flexibility changes in high-throughput structure probing data, showing higher sensitivity and fewer false positives than existing methods.

The paper identifies Hfq-mediated sRNA-target interactions in E. coli that facilitate adaptation to nutrient availability changes.

The paper introduces a new method, PTex, to purify RNA-protein complexes without relying on polyadenylated RNA, and provides a global RNA-bound proteome for human and bacterial cells.

This study identifies the PRY/SPRY domain of TRIM25 as its RNA-binding region and shows its role in ubiquitination.