Author

Emanuele Paoli

Champalimaud FoundationORCID 0009-0004-4886-9343Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:zebrafish· 2 Research Focus:cell-cell communication· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Rubén PortuguesiD· 3 shared Virginia PalieriiD· 2 shared Alexandra Mezydlo· 1 shared Amey Shenoy· 1 shared Christian HaassiD· 1 shared Christina Koupoutidou· 1 shared Chu Lan LaoiD· 1 shared Conny Kopp‐ScheinpflugiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersNeuroscience

Rubén PortuguesORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Modulation of habenula axon terminals supports action-outcome associations in larval zebrafish

Emanuele Paoli, Virginia Palieri, Amey Shenoy, Rubén Portugues

The paper shows that the dHb-IPN pathway in larval zebrafish is necessary for short-term action-outcome associations and that GABAB receptor-mediated modulation of dHb axon terminals integrates motor and sensory signals.

Nature Communications · Aug 7, 2026Peer-reviewedNeuroscience

Multimodal synapse analysis reveals limitations in transplanted neuron integration mediated by TREM2

Yvette Zarb, Oskar Markkula, Eva-Maria Schentarra, Manja Thorwirth, María Fernanda Martínez-Reza, Emanuele Paoli, Maria Richter, Mihail Ivilinov Todorov, Christina Koupoutidou, Veronika Schwarz, Georg Kislinger, Alexandra Mezydlo, Chu Lan Lao, Matteo Puglisi, Michael Willem, , Magdalena Götz

This study shows that TREM2 deficiency rescues synaptic integration and functional maturation of transplanted neurons in an inflammatory environment.

bioRxiv · Jan 31, 2025 · PreprintNeuroscience

The Preoptic Area and Dorsal Habenula Jointly Support Homeostatic Navigation in Larval Zebrafish

Virginia Palieri, Emanuele Paoli, You Kure Wu, Martin Haesemeyer, Ilona C Grunwald Kadow, Rubén Portugues

This study identifies a neural network connecting the preoptic area and habenula in larval zebrafish that supports thermoregulation through movement and spatial navigation.

Current Biology · Jan 10, 2024Peer-reviewedNeuroscience