Yangyang Wu

Microbes suppress genetic disorders of hyper-activated Ras by inhibiting iron-mediated growth factor modulation in C. elegans

The paper identifies E. coli mutants that suppress Ras(gf)-induced vulval defects in C. elegans by modulating iron availability and EGF signaling.

Head dopaminergic and serotonergic neurons monitor alterations in gut bacterial activity through a gut-brain-gut axis

The paper identifies E. coli genes whose inactivation is detected by C. elegans head neurons through changes in host iron metabolism and mitochondrial function, revealing a gut-brain-gut axis.

A novel fibrinogen gamma-chain mutation, p. γAla327Val, causes structural abnormality of D region and ultimately leads to congenital dysfibrinogenemia

This study identifies a novel γAla327Val mutation in the FGG gene causing congenital dysfibrinogenemia by altering fibrinogen structure and function.