Author

Xiaowen Huang

Shanghai Jiao Tong University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Chen Guang YangiD· 1 shared Cun WangiD· 1 shared Guanqun LiiD· 1 shared Hailin Zhang· 1 shared Hongyun TangiD· 1 shared Hualian Hang· 1 shared Hui WangiD· 1 shared Jun Wang· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioinformatics

Chen Guang YangORCID

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2 papers

Recent·Most cited

Head dopaminergic and serotonergic neurons monitor alterations in gut bacterial activity through a gut-brain-gut axis

Guanqun Li, Yangyang Wu, Xiaowen Huang, Minghui Du, Hongyun Tang

The paper identifies E. coli genes whose inactivation is detected by C. elegans head neurons through changes in host iron metabolism and mitochondrial function, revealing a gut-brain-gut axis.

bioRxiv · Jun 17, 2024 · PreprintDevelopmental Biology

A survey of optimal strategy for signature-based drug repositioning and an application to liver cancer

Chen Guang Yang, Hailin Zhang, Mengnuo Chen, Siying Wang, Ruolan Qian, Linmeng Zhang, Xiaowen Huang, Jun Wang, Zhicheng Liu, Wenxin Qin, Cun Wang, Hualian Hang, Hui Wang

This study identifies an optimal strategy for drug repositioning using LINCS data and applies it to discover new therapeutics for liver cancer, showing homoharringtonine as a promising candidate.

eLife · Feb 18, 2022Peer-reviewedBioinformatics