Hongyun Tang

Microbes suppress genetic disorders of hyper-activated Ras by inhibiting iron-mediated growth factor modulation in C. elegans

The paper identifies E. coli mutants that suppress Ras(gf)-induced vulval defects in C. elegans by modulating iron availability and EGF signaling.

A gentle palette of plasma membrane dyes

This paper introduces PK Mem dyes for time-lapse fluorescence imaging, showing reduced phototoxicity and improved photostability for live and fixed cell imaging.

Head dopaminergic and serotonergic neurons monitor alterations in gut bacterial activity through a gut-brain-gut axis

The paper identifies E. coli genes whose inactivation is detected by C. elegans head neurons through changes in host iron metabolism and mitochondrial function, revealing a gut-brain-gut axis.

Identification of BiP as a temperature sensor mediating temperature-induced germline sex reversal

The paper identifies BiP as a temperature sensor that mediates temperature-induced germline sex reversal in C. elegans by transducing temperature signals into germline sex determination.

Rapid Directed Molecular Evolution of Fluorescent Proteins in Mammalian Cells

This paper describes a method for rapidly optimizing fluorescent proteins in mammalian cells, resulting in enhanced near-infrared fluorescent proteins with improved intracellular brightness and multicolor imaging capabilities.