Author

Kent L. Nastiuk

Roswell Park Comprehensive Cancer CenterORCID 0009-0004-5253-1169Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Gurkamal S. ChattaiD· 3 shared Anmbreen JamrozeiD· 2 shared Dean G. TangiD· 2 shared Han Yu· 2 shared Igor J. PuzanoviD· 2 shared Jason S. KirkiD· 2 shared Kevin LiniD· 2 shared Wen Jess LiiD· 2 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Gurkamal S. ChattaORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologyMolecular CancerPeer-reviewedOct 27, 2026

Increasing Cancer Stemness Drives Prostate Cancer Progression, Plasticity, Therapy Resistance and Poor Patient Survival

Xiaozhuo Liu, Anmbreen Jamroze, Eduardo Cortes…·Dean G. Tang

This study quantifies cancer stemness in prostate cancer across progression stages, showing its association with therapy resistance, poor survival, and lineage plasticity.

1 citation

humanbulk RNA-seq

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Cancer BiologySignal Transduction and Targeted TherapyPeer-reviewedMay 1, 2026

Cell-resolved high-dimensional imaging analysis, therapeutic modeling, and a Phase Ib clinical study validate BCL-2 as a target across heterogeneous CRPC subtypes

Anmbreen Jamroze, Xiaozhuo Liu, Surui Hou…·Dean G. Tang

This study validates BCL-2 as a therapeutic target in CRPC by showing its upregulation under AR inhibition and demonstrating efficacy of BCL-2 inhibitors in preclinical and clinical models.

1 citation

humanimaging

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Cancer BiologybioRxivPreprintDec 1, 2023

Androgen deprivation triggers a cytokine signaling switch to induce immune suppression and prostate cancer recurrence

Kai Sha, R. Zhang, Aerken Maolake…·John J. Krolewski

1 citation

mouseexperimental assay

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