Eusondia Arnett

Timing matters in Macrophage / CD4+ T cell interactions: An agent-based model comparing Mycobacterium tuberculosis host-pathogen interactions between latently infected and naïve individuals

This paper develops an agent-based model to simulate immune responses to Mycobacterium tuberculosis infection, showing that early macrophage-CD4+ T cell interactions in latent TB infection reduce bacterial load through TNF and IFNγ mechanisms.

Human alveolar macrophage response to Mycobacterium tuberculosis: immune characteristics underlying large inter-individual variability

The paper examines inter-individual variability in human alveolar macrophage responses to Mycobacterium tuberculosis by analyzing gene and protein expression over time.