Maximilian F. Madern

This study uses live-cell single-molecule imaging to show that proteasome substrate processing depends on engagement mode, not just substrate identity or folding.

This study uses single-ribosome imaging and simulations to show that transient ribosome collisions promote efficient translation by suppressing ribosome pausing and recycling.

This study develops socRNA imaging to track single ribosomes, revealing ribosomal heterogeneity and translation elongation fidelity.