PITPβ promotes COPI vesicle fission through lipid transfer and membrane contact formation
Kunyou Park, Sungeun Ju, Hyewon Choi, Peng Gao, Geul Bang, Jung Hoon Choi, Jiwon Jang, Andrew J. Morris, Byung‐Ho Kang, Victor W. Hsu, Seung‐Yeol Park
The paper identifies PITPβ's role in COPI vesicle fission by delivering phosphatidylcholine through membrane contacts, revealing a mechanism for lipid transfer in intracellular transport.
The Journal of Cell Biology · Feb 19, 2025Peer-reviewedCell Biology