Author

Andrea Lacigová

Masaryk UniversityORCID 0009-0004-7001-4376Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Lukáš ČajánekiD· 2 shared Alison Donnelly AxtmaniD· 1 shared Frances M. BashoreiD· 1 shared Haoxi LiiD· 1 shared Raymond G. FlaxiD· 1 shared Stefanie HowelliD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

Lukáš ČajánekORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 12, 2026

An Analog-Sensitive Tau Tubulin Kinase 2 Enables Acute Chemical-Genetic Control of Primary Cilia

Andrea Lacigová, Lukáš Čajánek

This paper introduces an analog-sensitive TTBK2 variant to enable precise control of TTBK2 kinase activity, revealing dynamics of ciliary processes in hTERT-RPE1 cells.

DOI 10.64898/2026.10.09.757601

humanexperimental assay

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Cell BiologybioRxivPreprintApr 28, 2026

Development of Potent and Cell Active 5-Azaindole-Based Tau Tubulin Kinase Inhibitors

Raymond G. Flax, Andrea Lacigová, Stefanie Howell…·Alison Donnelly Axtman

This study develops and characterizes a potent and cell-active inhibitor of TTBK1 and TTBK2, with selectivity and potential therapeutic applications for neurodegenerative diseases.

2 citations

experimental assaydrug response / drug discovery

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