Lukáš Čajánek

This paper introduces an analog-sensitive TTBK2 variant to enable precise control of TTBK2 kinase activity, revealing dynamics of ciliary processes in hTERT-RPE1 cells.

This study develops and characterizes a potent and cell-active inhibitor of TTBK1 and TTBK2, with selectivity and potential therapeutic applications for neurodegenerative diseases.

This study identifies KIF14 as a non-canonical kinesin-3 motor that regulates intraflagellar transport in primary cilia by interacting with its motor domain and C-terminal CC1 domain.