Author

Georg Kosche

Institute of Molecular and Clinical Ophthalmology BaselORCID 0009-0004-7145-5720Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Botond RoskaiD· 2 shared Martin MunziD· 2 shared Alex FratzliD· 1 shared Alexandra C. Brignall· 1 shared Alexandra Graff-MeyeriD· 1 shared Arjun BhariokeiD· 1 shared Balázs József RózsaiD· 1 shared Brigitte Gross Scherf· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersNeuroscience

Botond RoskaORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 13, 2025

In vivo single-cell gene editing using RNA electroporation reveals sequential adaptation of cortical neurons to excitatory-inhibitory imbalance

Georg Kosche, Alex Fratzl, Martin Munz, Botond Roska

The paper uses RNA electroporation to knock out GABA-A receptor β subunits in cortical neurons, revealing sequential adaptation mechanisms to excitatory-inhibitory imbalance.

DOI 10.1101/2025.09.13.672380

mousescRNA-seq

𝕏 PostBluesky

NeuroscienceCellPeer-reviewedApr 1, 2023

Embryonic cortical layer 5 pyramidal neurons form an active, transient circuit motif perturbed by autism-associated mutations

Martin Munz, Arjun Bharioke, Georg Kosche…·Botond Roska

49 citationstop 3%

mousescRNA-seq

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