Author

Aswathy C. Sagilkumar

Regional Centre for BiotechnologyORCID 0009-0004-7182-2455Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

Frequent Co-Authors

Karthik SubramanianiD· 2 shared Aan RuthiD· 1 shared Anushka ShitutiD· 1 shared Avinashi Lal KushwahaiD· 1 shared Ayyanraj NeeraviiD· 1 shared Balaji Veeraragavan· 1 shared Charmi M. Panchal· 1 shared Dheeraj Kumar SarkariD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

Karthik SubramanianORCID

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2 papers

Recent·Most cited

MicrobiologyJournal of Extracellular VesiclesPeer-reviewedSep 30, 2026

Extracellular vesicle-bound bacterial toxin pneumolysin triggers membrane engagement and damage beyond canonical pore formation

Aswathy C. Sagilkumar, Avinashi Lal Kushwaha, Anushka Shitut…·Karthik Subramanian

This study shows that pneumolysin, a bacterial toxin, can damage target cell membranes through vesicle fusion rather than pore formation.

1 citation

humanproteomics

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MicrobiologymBioPeer-reviewedJun 16, 2026

Sorafenib, a clinically approved kinase inhibitor attenuates Streptococcus pneumoniae pathogenesis in vivo by targeting serine/threonine kinase StkP

Joel Abraham, Aswathy C. Sagilkumar, Himani Dhyani…·Karthik Subramanian

This study shows that sorafenib, a cancer drug, targets StkP in Streptococcus pneumoniae, reducing bacterial pathogenesis and mortality in mice.

1 citation

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