Seipin forms a flexible cage at lipid droplet formation sites
Henning Arlt, Xuewu Sui, Brayden Folger, Carson Adams, Xiao Chen, Roman Remme, Fred A. Hamprecht, Frank DiMaio, Maofu Liao, Joel M. Goodman, Robert V. Farese, Tobias C. Walther
This paper reports the structure of yeast seipin, revealing a decameric cage that facilitates lipid droplet formation through conformational changes.
Nature Structural & Molecular Biology · Feb 24, 2022Peer-reviewedMolecular Biology