Cancer BiologyNature ImmunologyPeer-reviewed
BACH2 dosage establishes the hierarchy of stemness and finetunes antitumor immunity in CAR T cells
Taidou Hu, Ziang Zhu, Luo Ying…·Tuoqi Wu
This study shows that BACH2 dosage regulates stemness hierarchy and antitumor immunity in CAR T cells, with tunable control improving therapeutic outcomes.