Author

Chen Yao

Harold C. Simmons Comprehensive Cancer CenterORCID 0000-0001-6852-5661Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Chen Yao2 papers · Ghent University

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

Tuoqi WuiD· 3 shared Taidou HuiD· 2 shared Abigail E. EllisiD· 1 shared Amy Jo JohnsoniD· 1 shared Brandon M. OswaldiD· 1 shared Connie M. KrawczykiD· 1 shared Hyoungjoo LeeiD· 1 shared Ibukunoluwa SodiyaiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

Tuoqi WuORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer BiologyNature ImmunologyPeer-reviewedJan 16, 2026

BACH2 dosage establishes the hierarchy of stemness and finetunes antitumor immunity in CAR T cells

Taidou Hu, Ziang Zhu, Luo Ying…·Tuoqi Wu

This study shows that BACH2 dosage regulates stemness hierarchy and antitumor immunity in CAR T cells, with tunable control improving therapeutic outcomes.

14 citationstop 1%

𝕏 PostBluesky

Cancer BiologyCancer Immunology ResearchPeer-reviewedOct 13, 2025

Single-cell clonal lineage tracing identifies the transcriptional program controlling the cell fate decisions by neoantigen-specific CD8+ T cells

Ying Luo, Taidou Hu, Chen Yao, Tuoqi Wu

This study uses single-cell transcriptomics and TCR profiling to identify the transcriptional program governing cell fate decisions in neoantigen-specific CD8+ T cells and its clinical relevance.

1 citation

𝕏 PostBluesky

ImmunologyNature ImmunologyPeer-reviewedJun 27, 2025

NRF2-dependent regulation of the prostacyclin receptor PTGIR drives CD8 T cell exhaustion

Michael S. Dahabieh, Lisa M. DeCamp, Brandon M. Oswald…·Russell G. Jones

This study identifies the KEAP1-NRF2 pathway as a driver of CD8 T cell exhaustion by regulating the prostacyclin receptor PTGIR.

31 citationstop 1%

humanbulk RNA-seq

𝕏 PostBluesky