Kristof Williams

This paper integrates multi-omics data across species to show AKI-induced lung alterations, identifying conserved pathways and human-validated targets for distant organ failure.

This study shows that targeted delivery of low-dose prednisolone via collagen IV 3-targeted nanoparticles reduces lupus nephritis in MRL/lpr mice.

This study develops glomerulus-targeted nanotherapy using collagen IV-α3 binding peptides to improve renal function and reduce inflammation in lupus nephritis.

This study shows that acute kidney injury increases SerpinA3N in the heart, which inhibits serine protease activity and promotes cardiac fibrosis and remodeling.