Glomerular-Targeted Delivery of Low-Dose Prednisolone Attenuates Established Lupus Nephritis in MRL/lpr Mice.
Kristof Williams, Georgina Agyekum, Akshata Patne, Eleni Markoutsa, David Raj Chellappan, Nathan Hall, Zhi Tian, Nohely Hernandez Soto, Sebastian Cuadrao, Isabella Lozonschi, Liying Fu, Lilliana Haight, Rahul Sharma, Subhra Mohapatra, Lei Wang, , Ruisheng Liu
This study shows that targeted delivery of low-dose prednisolone via collagen IV 3-targeted nanoparticles reduces lupus nephritis in MRL/lpr mice.
bioRxiv · Aug 6, 2026 · PreprintPhysiology