Author

David Raj Chellappan

University of South Florida

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Georgina AgyekumiD· 2 shared Isabella Lozonschi· 2 shared Kristof WilliamsiD· 2 shared Nathan Hall· 2 shared Nohely Hernandez Soto· 2 shared Ruisheng LiuiD· 2 shared Sebastian Cuadrao· 2 shared Zhi TianiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersPhysiology

Georgina AgyekumORCID

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Author profile →

3 papers

Recent·Most cited

Cross-species multi-omics integration reveals lung alterations in acute kidney injury across mouse, pig, and human airway organoid models

Zhi Tian, Nohely Hernandez Soto, Diane Allen‐Gipson, Georgina Agyekum, Xiaoqi Sun, Nadezhda N. Zheleznova, David Raj Chellappan, Nathan Hall, Kristof Williams, Runze Ni, Yuqian Tian, Sebastian Cuadrao, Vijay Subramanian, Lucian Lozonschi, Kiran K. Dhanireddy, , Ruisheng Liu

This paper integrates multi-omics data across species to show AKI-induced lung alterations, identifying conserved pathways and human-validated targets for distant organ failure.

bioRxiv · Oct 16, 2026 · PreprintPhysiology

Glomerular-Targeted Delivery of Low-Dose Prednisolone Attenuates Established Lupus Nephritis in MRL/lpr Mice.

Kristof Williams, Georgina Agyekum, Akshata Patne, Eleni Markoutsa, David Raj Chellappan, Nathan Hall, Zhi Tian, Nohely Hernandez Soto, Sebastian Cuadrao, Isabella Lozonschi, Liying Fu, Lilliana Haight, Rahul Sharma, Subhra Mohapatra, Lei Wang, , Ruisheng Liu

This study shows that targeted delivery of low-dose prednisolone via collagen IV 3-targeted nanoparticles reduces lupus nephritis in MRL/lpr mice.

bioRxiv · Aug 6, 2026 · PreprintPhysiology

Customized feminine hygiene wash containing postbiotics from Lactobacillus spp. to treat Urinary Tract Infections (UTI)

Veena G Nair, David Raj Chellappan, Remya Devi Durai, Rajesh B. R. D. Yamajala, Dhiviya Narbhavi, M. G. Anupriya, Nagarajan Prabhusaran, Saisubramanian Nagarajan

This paper develops and evaluates a postbiotics vaginal wash using metabolites from Lactobacillus spp. to prevent UTIs, showing in vitro and preclinical efficacy against uropathogenic bacteria.

bioRxiv · Jan 24, 2025 · PreprintMicrobiology