Cutting in-line with iron: ribosomal function and non-oxidative RNA cleavage
Rebecca Guth-Metzler, Marcus S. Bray, Moran Frenkel‐Pinter, Suttipong Suttapitugsakul, Claudia Montllor-Albalate, Jessica C. Bowman, Ronghu Wu, Amit R. Reddi, C. Denise Okafor, Jennifer B. Glass, Loren Dean Williams
The paper demonstrates that Fe2+ cleaves RNA via a non-oxidative in-line mechanism, is more reactive than Mg2+, and is stably associated with ribosomes under anaerobic conditions.
Nucleic Acids Research · Jun 30, 2020Peer-reviewedMolecular Biology