The microbial metabolite p-Cresol induces autistic-like behaviors in mice by remodeling the gut microbiota
Patricia Bermudez-Martin, Jérôme A. J. Becker, Nicolas Caramello, Sebastián P. Fernández, Renan Costa Campos, Juliette Canaguier, Susana Barbosa, Laura Martínez-Gili, Antonis Myridakis, Marc‐Emmanuel Dumas, Aurélia Bruneau, Claire Cherbuy, Philippe Langella, Jacques Callebert, Jean‐Marie Launay, , Laëtitia Davidovic
This study shows that p-Cresol, a microbial metabolite more abundant in ASD patients, induces ASD-like behaviors in mice through gut microbiota-dependent mechanisms.
Microbiome · Jul 8, 2021Peer-reviewedNeuroscience