Ex vivo and in vivo CRISPR/Cas9 screenings identify the roles of protein N-glycosylation in regulating T-cell activation and functions
Yu Hong, Xiaofang Si, Wenjing Liu, Xueying Mai, Yu Zhang
The paper identifies B4GALT1 as a regulator of CD8+ T-cell function through N-glycosylation, showing its potential as a target for immunotherapy.
bioRxiv · Aug 20, 2025Immunology