Author

Martin O’Brien

University of MichiganORCID 0009-0004-8712-1629Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Archit KumariD· 2 shared Raymond L. YungiD· 2 shared Vincent Bensan YoungiD· 2 shared Alexandra K. StandkeiD· 1 shared Hannah Ruppel· 1 shared Ingrid L. BerginiD· 1 shared Ivy Earl· 1 shared Kimberly C. VendroviD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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2 shared papersMicrobiology

Archit KumarORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintJan 5, 2026

High-fat diet rewires gut host-microbiota relationship to derive worse outcomes following Clostridioides difficile infection

Archit Kumar, N. M. Nguyen, Martin O’Brien…·Raymond L. Yung

This study shows high-fat diets worsen outcomes of Clostridioides difficile infection in mice by altering immune responses and gut microbiota.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologyAging CellPeer-reviewedOct 21, 2025

Single-cell RNA sequencing identifies accumulation of Fcgr2b+ virtual memory like CD8 T cells with cytotoxic and inflammatory potential in aged mouse white adipose tissue

Archit Kumar, Martin O’Brien, Vincent Bensan Young, Raymond L. Yung

6 citations

𝕏 PostBluesky