BiochemistryScience SignalingPeer-reviewed
Autophosphorylation of the oncogenic protein TEL-ABL confers resistance to the allosteric ABL inhibitor asciminib
Serena Muratcioğlu, Christopher A. Eide, Chien‐Lun Hung…·John Kuriyan
The paper shows that phosphorylation of TEL-ABL makes it resistant to asciminib, but dephosphorylation restores sensitivity.
3 citations