Author

Serena Muratcioğlu

Vanderbilt UniversityORCID 0000-0002-5983-294XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

John KuriyaniD· 3 shared Jay T. GrovesiD· 2 shared Axel T. BrüngeriD· 1 shared Baiyu QiuiD· 1 shared Brian J. DrukeriD· 1 shared Chien‐Lun HungiD· 1 shared Christopher A. EideiD· 1 shared Chuchu WangiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersMicrobiology

John KuriyanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A rational design strategy and validation for protease-resistant fusion-inhibitor antiviral peptides

Kailu Yang, Chuchu Wang, Francesco Topi, Serena Muratcioğlu, Ravi Kant, Tomas M. Strandin, Yih Tyng Bong, Lauri Kareinen, Sanna Mäki, Saber H. Saber, Tobias Binder, Tarja A. Sironen, Subu K. Subramanian, K. Ian White, Richard A. Pfuetzner, , Axel T. Brünger

This study designs and validates protease-resistant antiviral peptides that inhibit SARS-CoV-2 fusion, showing improved efficacy in vitro and in vivo.

bioRxiv · Nov 2, 2026 · PreprintMicrobiology

Autophosphorylation of the oncogenic protein TEL-ABL confers resistance to the allosteric ABL inhibitor asciminib

Serena Muratcioğlu, Christopher A. Eide, Chien‐Lun Hung, Kent Gorday, Emily Sumpena, Wenqi Zuo, Jay T. Groves, Brian J. Druker, John Kuriyan

The paper shows that phosphorylation of TEL-ABL makes it resistant to asciminib, but dephosphorylation restores sensitivity.

Science Signaling · Jul 15, 2025Peer-reviewedBiochemistry

Breakage of the Oligomeric CaMKII Hub by the Regulatory Segment of the Kinase

Deepti Karandur, Moitrayee Bhattacharyya, Zijie Xia, Young Kwang Lee, Serena Muratcioğlu, Darren B. McAffee, Ethan D. McSpadden, Baiyu Qiu, Jay T. Groves, Evan R. Williams, John Kuriyan

The paper shows that the regulatory segment of CaMKII can break the oligomeric hub into smaller assemblies through binding and structural destabilization.

eLife · Sep 9, 2020Peer-reviewedBioinformatics