Revisiting AXL as a therapeutic target in soft tissue sarcoma: transcriptomic profiling reveals largely AXL-independent activity of dubermatinib and bemcentinib
Cristina Garnés‐García, Pablo Fernández‐Aroca, Francisco J. Cimas, María José Ruiz‐Hidalgo, Borja Belandia, Noelia Mayor-Garnacho, António Fernández, Victor Javier Sanchez-Arevalo Lobo, Ricardo Sánchez‐Prieto, Diego M. Fernández‐Aroca
This study shows that AXL inhibitors dubermatinib and bemcentinib have antitumour effects in soft tissue sarcoma that are largely independent of AXL inhibition.
bioRxiv · Oct 15, 2026 · PreprintCancer Biology