Author

Tomoyuki Wakashima

University of TsukubaORCID 0009-0004-9476-4454Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:metabolomics· 2 Research Focus:phylogenetics / evolution· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Yoko ChibaiD· 3 shared Shigeru ShimamuraiD· 2 shared Takuro NunouraiD· 2 shared Yuto FukuyamaiD· 2 shared Keitaro KumeiD· 1 shared Ken TakaiiD· 1 shared Masafumi KameyaiD· 1 shared Ryoma KamikawaiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersMicrobiology

Yoko ChibaORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Direct carbon monoxide fixation via the bacterial and archaeal Wood-Ljungdahl pathways

Yuto Fukuyama, Sanae Sakai, Yoko Chiba, Shigeru Shimamura, Satoshi Hiraoka, Tomoyuki Wakashima, Takuro Nunoura, Ken Takai

The paper shows direct CO fixation to acetyl-CoA in archaeal and bacterial Wood-Ljungdahl pathways under hydrogenogenic growth using 13C tracer-based metabolomics.

bioRxiv · Oct 29, 2025 · PreprintMicrobiology

Molecular evolution of the Wood-Ljungdahl pathway and the reductive glycine pathway in Thermodesulfobacteriota

Tomoyuki Wakashima, Keitaro Kume, Yoko Chiba

The paper investigates the evolutionary history of carbon fixation pathways in Thermodesulfobacteriota, finding that their common ancestor had both the Wood-Ljungdahl and reductive glycine pathways, with subsequent gene loss and horizontal gene transfer shaping current diversity.

bioRxiv · Sep 1, 2025 · PreprintBioinformatics

Impact of acetate on CO2 fixation pathways in thermophilic and hydrogenotrophic bacteria

Yoko Chiba, Tomomi Sumida, Masafumi Kameya, Yuto Fukuyama, Tomoyuki Wakashima, Shigeru Shimamura, Ryoma Kamikawa, Yoshito Chikaraishi, Takuro Nunoura

This study examines how acetate affects CO2 fixation pathways in thermophilic bacteria, showing acetate suppresses the WL pathway and promotes the rTCA cycle in some species.

ISME Communications · Jan 1, 2025Peer-reviewedMicrobiology