Author

Sanae Sakai

Japan Agency for Marine-Earth Science and Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Ken TakaiiD· 2 shared Shigeru ShimamuraiD· 2 shared Akihiro NaritaiD· 1 shared Anne DaebeleriD· 1 shared Eiji TasumiiD· 1 shared Eva PetrováiD· 1 shared Hiroki HashiguchiiD· 1 shared Hiroyuki ImachiiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMicrobiology

Ken TakaiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Eukaryotes' closest relatives are internally simple syntrophic archaea

Hiroyuki Imachi, Masaru Konishi Nobu, Shun’ichi Ishii, Hiroki Hashiguchi, Yuga Hirakata, Naoki Hosogi, Tetsuro Ikuta, Yuta Isaji, Makoto Miyata, Masayuki Miyazaki, Yuki Morono, Kazuyoshi Murata, Satoshi Okada, Akihiro Narita, Miyuki Ogawara, , Ken Takai

This study isolates two Hodarchaeales strains, closely related to the eukaryotic common ancestor, revealing their syntrophic, anaerobic, and oxygen-tolerant physiology and genomic features.

Nature · Oct 28, 2026Peer-reviewedMicrobiology

Direct carbon monoxide fixation via the bacterial and archaeal Wood-Ljungdahl pathways

Yuto Fukuyama, Sanae Sakai, Yoko Chiba, Shigeru Shimamura, Satoshi Hiraoka, Tomoyuki Wakashima, Takuro Nunoura, Ken Takai

The paper shows direct CO fixation to acetyl-CoA in archaeal and bacterial Wood-Ljungdahl pathways under hydrogenogenic growth using 13C tracer-based metabolomics.

bioRxiv · Oct 29, 2025 · PreprintMicrobiology

Cultivation and genomic characterisation of novel methanogens from a desert biocrust

Weitao Tian, Eva Petrová, Sanae Sakai, Julius Eyiuche Nweze, Anne Daebeler, Roey Angel

This study cultivates and genomes seven new methanogenic cultures from desert biocrusts, revealing their genetic adaptations to oxic and arid environments.

bioRxiv · Sep 22, 2025 · PreprintMicrobiology