Author

Ellis Nicholson

University of YorkORCID 0009-0004-9482-8980Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Adam Sung· 1 shared Barwin ViswanathaniD· 1 shared Callum RobsoniD· 1 shared Christopher D. SpiceriD· 1 shared Dave BoucheriD· 1 shared James P. KleppeniD· 1 shared Kaiwen W. CheniD· 1 shared Pranav Patel· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Adam Sung

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1 paper

Recent·Most cited

Evolution of a Pyroptosis-Apoptosis crosstalk drives non-canonical inflammasome signalling.

Sebastian Grant, Ellis Nicholson, Zoe Hui Xin Chen, Callum Robson, Adam Sung, Barwin Viswanathan, Yunjia Chang, Pranav Patel, James P. Kleppen, Timur Ozdenya, Kaiwen W. Chen, Christopher D. Spicer, Dave Boucher

This study identifies a novel mechanism by which caspase-4 and -5 interact with executioner caspases-3 and -7 to enable pyroptosis-apoptosis crosstalk, enhancing inflammatory responses.

bioRxiv · Nov 1, 2025 · PreprintBiochemistry