Author

Kaiwen Chen

National University of SingaporeORCID 0000-0001-5903-3251Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Kaiwen Chen1 paper · Johns Hopkins University

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Aarthi Nivasini MaheshiD· 1 shared Adam Sung· 1 shared Barwin ViswanathaniD· 1 shared Callum RobsoniD· 1 shared Christopher D. SpiceriD· 1 shared Dave BoucheriD· 1 shared Ellis NicholsoniD· 1 shared James P. KleppeniD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Aarthi Nivasini MaheshORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintNov 1, 2025

Evolution of a Pyroptosis-Apoptosis crosstalk drives non-canonical inflammasome signalling.

Sebastian Grant, Ellis Nicholson, Zoe Hui Xin Chen…·Dave Boucher

This study identifies a novel mechanism by which caspase-4 and -5 interact with executioner caspases-3 and -7 to enable pyroptosis-apoptosis crosstalk, enhancing inflammatory responses.

DOI 10.1101/2025.11.01.685735

humanproteomics

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Cancer BiologybioRxivPreprintNov 17, 2023

DFNA5-mediated pyroptosis is a driver for venetoclax and azacytidine synergy in myeloid leukemia

Aarthi Nivasini Mahesh, Joanne Lai Xin-Yi, Mandy Tng Jia Lin…·Shruti Bhatt

This study shows that DFNA5-mediated pyroptosis contributes to the synergy between venetoclax and azacytidine in myeloid leukemia, beyond apoptosis.

DOI 10.1101/2023.11.17.567421

humanbulk RNA-seq

𝕏 PostBluesky