Author

Sarah Byrne

Ollscoil na Gaillimhe – University of GalwayORCID 0009-0004-9800-5500Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Assay:metagenomics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaron Christopher NolaniD· 1 shared James P. O’GaraiD· 1 shared Merve Suzan ZedeniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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1 shared paperMicrobiology

Aaron Christopher NolanORCID

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1 paper

Recent·Most cited

MicrobiologybioRxivPreprintMay 25, 2026

Purine and pyrimidine analogues differentially regulate cell wall precursor biosynthesis to control β-lactam susceptibility in methicillin resistant Staphylococcus aureus

Aaron Christopher Nolan, Sarah Byrne, Merve Suzan Zeden, James P. O’Gara

This paper shows that pyrimidine analogues enhance β-lactam antibiotics against MRSA by altering cell wall precursor biosynthesis, while the purine analogue 6-TG has antagonistic effects.

DOI 10.64898/2026.05.24.727567

bacteria (other)proteomics

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