Author

Adriana Morales Miranda

National Cancer InstituteORCID 0009-0005-0356-0235Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Mengyan ZhangiD· 2 shared Stephen Jacob ChanockiD· 2 shared Tongwu ZhangiD· 2 shared Bin ZhuiD· 1 shared Bin ZhuiD· 1 shared Guangyu Wang· 1 shared Haoyu ZhangiD· 1 shared Jacob WilliamsiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenomics

Mengyan ZhangORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintApr 7, 2026

Endogenous mutational mechanisms and metabolic context shape endometrial cancer

Jian Sang, Mengyan Zhang, Sergio Chavez…·Tongwu Zhang

This study identifies subtype-specific mutational mechanisms and links them to host metabolic factors in endometrial cancer using genomic and transcriptomic data from 440 tumors.

DOI 10.64898/2026.04.03.716356

humanwhole-genome sequencing

𝕏 PostBluesky

GenomicsbioRxivPreprintJun 12, 2025

A Thiopurine-like Mutagenic Process Defines TGCT Subtypes

Kevin M. Brown, Jun Zhong, Adriana Morales Miranda…·Tongwu Zhang

This study identifies a unique mutational signature, SBS87, in testicular germ cell tumors (TGCTs) that resembles thiopurine-induced DNA damage and is associated with tumor latency and telomere elongation.

1 citation

humanwhole-genome sequencing

𝕏 PostBluesky