Cancer BiologybioRxivPreprint
Co-targeting KRAS and BCL-2 induces pyroptosis and antitumor tertiary lymphoid structures
Xu Yang, Man Li, Jian Zhang…·Jie Wang
This study shows that combining KRAS and BCL-2 inhibition induces pyroptosis and tertiary lymphoid structures in KRAS G12D-mutant lung cancer, enhancing B-cell-dependent antitumor immunity.
DOI 10.64898/2026.10.12.756217