Molecular BiologyGenome biologyPeer-reviewed
Long-read Individual-molecule Sequencing Reveals CRISPR-induced Genetic Heterogeneity in Human ESCs
Chongwei Bi, Lin Wang, Baolei Yuan…·Mo Li
The paper develops a method to quantify rare genetic variants in human cells using long-read sequencing and shows CRISPR-Cas9 induces nonrandom large deletions and insertions.
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