Author
The University of Texas Southwestern Medical CenterORCID 0009-0005-2552-5852Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Candace Kelly, Binh An Nguyen, Virender Pratap Singh…·Lorena Saelices
The paper investigates structural polymorphism in ATTR amyloid fibrils from a fourth patient, extending previous findings of two cardiac polymorphs to other organs.
Shumaila Afrin, Binh An Nguyen, Parker T. Bassett…·Lorena Saelices
This study determines cryo-EM structures of brain-derived ATTR fibrils from patients with V30M and V30G variants, revealing distinct folds compared to peripheral tissues.
Yasmin Ahmed, Binh An Nguyen, Candace Kelly…·Lorena Saelices
The paper uses cryo-electron microscopy to characterize amyloid fibrils from the heart and liver of an ATTRv amyloidosis patient with the V122Δ mutation, finding structural polymorphism linked to polyneuropathy.