Author

Cerys S. McCool

Garvan Institute of Medical ResearchORCID 0009-0005-3055-704XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Christine Louise ChafferiD· 2 shared Aarthi VenkatiD· 1 shared Andrew BenziD· 1 shared Annelie MollbrinkiD· 1 shared Beatriz P. San JuaniD· 1 shared Carley A. PurcelliD· 1 shared Daisy KavanaghiD· 1 shared Daniel B. BurkhardtiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersGenomics

Christine Louise ChafferORCID

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2 papers

Recent·Most cited

GenomicsNucleic Acids ResearchPeer-reviewedFeb 4, 2026

Isoform-specific single-cell perturb-seq reveals distinct functions of alternative promoters in drug response

Helen E King, Savannah O’Connell, Daisy Kavanagh…·Robert J. Weatheritt

The paper uses isoform-specific single-cell Perturb-Seq to show that alternative promoters drive distinct transcriptional programs and affect drug response in breast cancer.

3 citationstop 4%

humanCRISPR screen

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BioinformaticsbioRxivPreprintMay 11, 2024

AAnet resolves a continuum of spatially-localized cell states to unveil tumor complexity

Aarthi Venkat, Scott E. Youlten, Beatriz P. San Juan…·Christine Louise Chaffer

AAnet identifies archetypal cell states in single-cell data to reveal tumor heterogeneity and spatial organization.

3 citations

humanscRNA-seq

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