Author

Helen E King

Garvan Institute of Medical Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Genomics· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Cerys S. McCooliD· 1 shared Christine Louise ChafferiD· 1 shared Daisy KavanaghiD· 1 shared Helaine Graziele Santos VieiraiD· 1 shared Javier Fernández-ChamorroiD· 1 shared Robert J. WeatherittiD· 1 shared Savannah O’ConnelliD· 1 shared Sofia MasoniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Cerys S. McCoolORCID

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1 paper

Recent·Most cited

Isoform-specific single-cell perturb-seq reveals distinct functions of alternative promoters in drug response

Helen E King, Savannah O’Connell, Daisy Kavanagh, Sofia Mason, Cerys S. McCool, Javier Fernández-Chamorro, Christine Louise Chaffer, Susan J. Clark, Helaine Graziele Santos Vieira, Timothy Sterne-Weiler, Robert J. Weatheritt

The paper uses isoform-specific single-cell Perturb-Seq to show that alternative promoters drive distinct transcriptional programs and affect drug response in breast cancer.

Nucleic Acids Research · Feb 4, 2026Peer-reviewedGenomics