Developmental BiologyProceedings of the National Academy of SciencesPeer-reviewed
Mad dephosphorylation at the nuclear envelope is essential for asymmetric stem cell division
Justin Sardi, Muhammed Burak Bener, Taylor Simao…·Mayu Inaba
The paper shows that Mad dephosphorylation at the nuclear envelope creates asymmetry in pMad levels between stem cells and differentiating daughter cells, preventing tumor formation.
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