Author

Viktoriya Lukasheva

Institute for Research in Immunology and CancerORCID 0000-0002-7364-0311Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Christian Le GouilliD· 2 shared Michel BouvieriD· 2 shared Anna Fassler BakhmaniD· 1 shared Arturo D. Mancini· 1 shared Boubacar Sidiki TraoreiD· 1 shared Hiroyuki KobayashiiD· 1 shared Laurent SabbaghiD· 1 shared Mickey KosloffiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 26 mutual co-author links

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2 shared papersCell Biology

Christian Le GouillORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintApr 3, 2026

Unconventional Interplay Between GPCRs and RTKs Signaling Pathways Through SH2 Domain-Containing Proteins

Pedro Henrique Scarpelli Pereira, Arturo D. Mancini, Boubacar Sidiki Traore…·Michel Bouvier

This study identifies a novel mechanism where Gq/11 and G12/13 activation causes SH2 domain-containing proteins to translocate from the plasma membrane to the nucleus, reducing RTK signaling activity.

DOI 10.64898/2026.04.02.716162

humanproteomics

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BiochemistrybioRxivPreprintDec 28, 2024

Molecular determinants underlying differential recruitment of p115RhoGEF and PDZRhoGEF to activated Gα13

Anna Fassler Bakhman, Viktoriya Lukasheva, Christian Le Gouill…·Michel Bouvier

This study identifies residue-level differences in G13 interactions with p115RhoGEF and PDZRhoGEF, revealing molecular determinants of their differential recruitment and providing insights for targeted therapeutic strategies.

DOI 10.1101/2024.12.28.630591

statistical modelexperimental assay

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