Author

Alex Fraser

Allen Institute for Brain ScienceORCID 0009-0005-3975-0962Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Organism:non-human primate· 1 Organism:rat· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Ananya ChowdhuryiD· 2 shared Boaz P. LeviiD· 2 shared Cindy Tzu-Ling HuangiD· 2 shared Dakota NewmaniD· 2 shared Ed S. LeiniD· 2 shared Elizabeth LiangiD· 2 shared Emily KussickiD· 2 shared Jonathan T. TingiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Ananya ChowdhuryORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintApr 27, 2026

Cell type-selective AADC expression reduces motor deficits and dyskinesia in Parkinson's disease mouse models

Ananya Chowdhury, Alex Fraser, Maxwell Departee…·Tanya L. Daigle

This study shows that cell type-specific AADC expression in Parkinson's disease models reduces motor deficits and dyskinesia more effectively than broad targeting.

DOI 10.64898/2026.01.20.700641

mouseexperimental assay

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NeuroscienceCell ReportsPeer-reviewedMay 21, 2025

Enhancer AAVs for targeting spinal motor neurons and descending motor pathways in rodents and macaque

Emily Kussick, Nelson Johansen, Naz Taskin…·Tanya L. Daigle

The paper identifies enhancers for spinal motor neurons and develops AAV vectors to target these cells in rodents and macaques, enabling functional studies and potential therapeutic applications.

27 citationstop 1%

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