Gonzalo N Morales Chaya

This study shows that cell cycle progression and cytokinesis are required for the early-to-late gene expression transition in Drosophila NSCs, alongside hormonal cues.

The paper uses single nuclei RNA sequencing to analyze transcriptional diversity of T2 neuroblast-derived neurons and glia in Drosophila, identifying clusters and transcription factor codes for neuron subtypes in the central complex.

This study identifies stem cell-specific ecdysone signaling as critical for generating sleep-promoting neurons in Drosophila and shows its impact on adult sleep behavior.