Author

John W. Smerdon

Columbia University Irving Medical CenterORCID 0009-0005-6801-9407Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Hynek WichterleiD· 2 shared Alexander S. GalkiniD· 1 shared Alon GelberiD· 1 shared Belem Yoval‐SáncheziD· 1 shared Christine VogeliD· 1 shared Delfina LarreaiD· 1 shared Disi AniD· 1 shared Dylan E. IannitelliiD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Hynek WichterleORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintSep 22, 2022

Altered MAM function shifts mitochondrial metabolism in SOD1-mutant models of ALS

Delfina Larrea, Kirstin A. Tamucci, Khushbu Kabra…·Estela Área-Gómez

This study shows that disrupted MAM function in ALS models leads to altered mitochondrial metabolism, specifically a shift from pyruvate to fatty acid utilization.

2 citations

humanmouse

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NeuroscienceeLifePeer-reviewedJun 3, 2019

Stem cell-derived cranial and spinal motor neurons reveal proteostatic differences between ALS resistant and sensitive motor neurons

Disi An, Ryosuke Fujiki, Dylan E. Iannitelli…·Esteban O. Mazzoni

The paper identifies proteostatic differences between ALS-resistant and sensitive motor neurons using stem cell-derived models.

43 citations

mouseexperimental assay

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