BiophysicsbioRxivPreprint
Lipidic α-synuclein fibrils catalyze the formation of pathological mature fibrils
Alisdair Stevenson, Jesper E. Dreier, Nina Baumgartner…·Thomas C. T. Michaels
This study shows lipidic α-synuclein fibrils catalyze the formation of mature fibrils through a heterogeneous nucleation mechanism, lowering the energy barrier and following Ostwald's Rule of Stages.
DOI 10.64898/2026.11.04.764198