Author

Jack W.J. Welland

University of CambridgeORCID 0009-0005-7805-1574Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Janet Elwyn DeaneiD· 2 shared Henry G. BarrowiD· 1 shared Phillip James StansfeldiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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2 shared papersBioinformatics

Janet Elwyn DeaneORCID

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2 papers

Recent·Most cited

BioinformaticsComputational and Structural Biotechnology JournalPeer-reviewedMar 1, 2026

Ensemble Machine Learning Approaches Predict Survival in Lower-Grade Glioma Based on Glycosphingolipid Gene Expression and Metabolic Modelling

Jack W.J. Welland, Janet Elwyn Deane

The paper uses ensemble machine learning with GSL gene expression and metabolic models to predict survival in lower-grade glioma patients, identifying associations with cell motility and Wnt signaling.

DOI 10.34133/csbj.0143

humanbulk RNA-seq

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BiochemistryNature CommunicationsPeer-reviewedJul 1, 2025

Conformational Dynamics and Membrane Insertion Mechanism of B4GALNT1 in Ganglioside Synthesis

Jack W.J. Welland, Henry G. Barrow, Phillip James Stansfeld, Janet Elwyn Deane

This study reveals the conformational dynamics and membrane insertion mechanism of B4GALNT1 in ganglioside synthesis using crystal structures and molecular simulations.

8 citations

humanstructural biology

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