Author

Chloe Ong

University of Nebraska–LincolnORCID 0009-0005-7894-2342Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Assay:structural biology· 2 Organism:bacteria (other)· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:phylogenetics / evolution· 1 Approach:statistical model· 1

Frequent Co-Authors

Limei ZhangiD· 2 shared Tao Wan· 2 shared Adrie J. C. SteyniD· 1 shared Camden Jones· 1 shared Daisy Guiza BeltraniD· 1 shared Donald BeckeriD· 1 shared Hongfeng YuiD· 1 shared Javier SeravalliiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBiochemistry

Limei ZhangORCID

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2 papers

Recent·Most cited

BiochemistryCommunications BiologyPeer-reviewedFeb 13, 2026

Aromatic Patch in WhiB-Like Transcription Factors Facilitates Primary Sigma Factor Interaction in Mycobacterium tuberculosis

Daisy Guiza Beltran, Tao Wan, Javier Seravalli…·Limei Zhang

This study identifies an aromatic patch in Mtb Wbl proteins that mediates interaction with the primary sigma 70 factor, revealing a conserved binding mechanism and evolutionary relationship with actinobacterial phages.

DOI 10.1038/s42003-026-09698-5

structural biologyexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivPreprintDec 27, 2025

A New Paradigm of Transcriptional Regulation by the SufR-Like Iron-Sulfur Transcription Factors

Zhifang Lu, Chloe Ong, Lingwen Zhang…·Limei Zhang

This study reveals the structural and functional mechanism of SufR-like iron-sulfur transcription factors in bacteria, showing a novel DNA recognition strategy and expanding their known evolutionary distribution.

DOI 10.64898/2025.12.26.696629

bacteria (other)structural biology

𝕏 PostBluesky