The resilience of Salmonella to bile stress is impaired due to the reduced efflux pump activity mediated by the antioxidant enzyme YqhD
Kirti S. Parmar, Yachna Kumari, Raju S Rajmani, Dipshikha Chakravortty
This study shows that YqhD in Salmonella reduces reactive oxygen species and efflux pump activity, impairing bile resistance, and that its mutation increases survival in bile stress conditions.