Dipshikha Chakravortty

Intracellular formate is a critical mediator of the antimicrobial fate of Salmonella Typhimurium Against meropenem and ciprofloxacin

This study identifies intracellular formate as a key mediator of antibiotic susceptibility in Salmonella Typhimurium, showing its role in pH homeostasis and efflux pump function.

Efficient elimination of microbial infections in wounds using plasma activated water hydrogel

The paper develops a neutral pH plasma-activated water hydrogel that effectively reduces microbial infections and promotes wound healing in mouse models.

Undecaprenyl Pyrophosphate Phosphatase (UppP) is a pivotal element in Salmonella Intramacrophage Survival

This study identifies UppP as essential for Salmonella survival in macrophages and systemic infection by enhancing resistance to nitrosative stress.

Eco-friendly approach to indenodiazepinones from o-formylynones and o-phenylenediamines: Novel pharmacophoric constructs and their anti-bacterial activity

This paper describes an eco-friendly one-pot synthesis of indenodiazepinones with antibacterial activity and reports their resistance properties against Salmonella Typhimurium.

Maltose aids in the growth of Salmonella Typhimurium in nitrogen-deficient conditions

This study shows maltose enhances Salmonella Typhimurium growth under nitrogen-deficient conditions but impairs its pathogenicity.

The resilience of Salmonella to bile stress is impaired due to the reduced efflux pump activity mediated by the antioxidant enzyme YqhD

This study shows that YqhD in Salmonella reduces reactive oxygen species and efflux pump activity, impairing bile resistance, and that its mutation increases survival in bile stress conditions.

Unravelling the Dynamics of Bacterial-Laden Respiratory Droplets: Epidemiological Transfer from Fomites to Susceptible Host

This study investigates how respiratory droplets containing Pseudomonas aeruginosa transfer pathogens via surfaces, finding increased viability with mucin and significant transfer at high humidity.

Evaporation and pathogenesis of levitated bacteria-laden surrogate respiratory fluid droplets: At different relative humidity and evaporation stages

This study examines how relative humidity and evaporation stages affect bacterial survival and infectivity in respiratory droplets under different evaporation modes.

Interbacterial AI-2 communication drives stage-specific genetic programs to support Salmonella colonisation in the murine gut

This study shows AI-2 signaling in Salmonella coordinates gene expression for colonization and virulence in mice, with potential for therapeutic targeting.

Maltose attenuates the virulence of Salmonella Typhimurium by impairing its entry into epithelial cells

This study shows maltose reduces Salmonella Typhimurium's ability to infect epithelial cells by decreasing adhesion through type 1 fimbriae.

Endoplasmic Reticulum contact sites facilitate the coordinated division of Salmonella-containing vacuole (SCV)

This study shows that Salmonella effector SteA promotes ER contact sites with SCVs to coordinate their division, ensuring single bacterium per vacuole.

Salmonella Typhimurium Manipulates Syntaxin 7 to Navigate Endo-Lysosomal Trafficking in Host Cells

This study shows Salmonella Typhimurium manipulates syntaxin 7 to alter endo-lysosomal trafficking, aiding its survival in host cells.

The quorum-sensing lexicon of Salmonella ameliorates acid stress in the host by a non-canonical mechanism

This study shows Salmonella Typhimurium uses AI-2 quorum sensing to enhance acid tolerance and survival in macrophages by modulating pH-sensing systems and SPI-2 regulators.

Salmonella effector SseL induces PD-L1 up-regulation and T cell inactivation via beta-catenin signalling axis

This study identifies Salmonella effector SseL as a key mediator of PD-L1 upregulation via beta-catenin signaling, leading to T cell inactivation and immune evasion.

Neutral pH Plasma-Activated Water eliminates ESKAPE pathogens via reactive nitrogen species with dual potential for surface sanitation and wound cleansing

This study develops neutral pH plasma-activated water (hs-PAbW) that kills ESKAPE pathogens via reactive nitrogen species, showing effectiveness for surface sanitation and wound cleansing without acidic conditions.

Odoribacter splanchnicus mitigates pathogen-induced gut inflammation and its associated pathogenesis via its secreted bacteriocin

This study identifies Odoribacter splanchnicus as a broad-spectrum protective agent against Salmonella and Listeria infections by enhancing colonization resistance, preserving gut barrier integrity, and limiting pathogen proliferation and virulence.