Cell BiologybioRxivPreprint
SOX8-USP7-PGC-1α axis enhances thermogenesis in brown adipocytes
Yuqin Gu, Ziheng Kan, Guangyu Lu…·Ziyan Wang
This study identifies a SOX8-USP7-PGC-1α regulatory axis in brown adipocytes that enhances thermogenesis but also causes metabolic maladaptation with prolonged activation.