Ziyan Wang

This paper shows that the fungal ATRX ortholog SAD-6 uses a unique histone H4 variant for genome surveillance and defense, revealing its role in various genomic regions and a repeat-induced point mutation pathway.

This study identifies a SOX8-USP7-PGC-1α regulatory axis in brown adipocytes that enhances thermogenesis but also causes metabolic maladaptation with prolonged activation.