Author

Grischa Ott

University of BernORCID 0009-0006-0974-7321Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:imaging· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Benoît ZuberiD· 2 shared Iman RostamiiD· 2 shared Jana Leuenberger· 2 shared Thomas NevianiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersNeuroscience

Benoît ZuberORCID

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2 papers

Recent·Most cited

NeuroscienceCell Death DiscoveryPeer-reviewedApr 14, 2026

Differentiated SH-SY5Y Cells Exhibit Neuronal Features but Lack Synaptic Maturity

Jana Leuenberger, Grischa Ott, Thomas Nevian…·Iman Rostami

The paper evaluates the synaptic maturity of SH-SY5Y cells after differentiation and finds they lack functional synapses despite some presynaptic features.

4 citationstop 2%

humanimaging

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NeurosciencebioRxivPreprintNov 11, 2025

Advancing Human iPSC-Derived Motor Neuron Models Using Glutamatergic Modulators for Synaptic Function Studies

Iman Rostami, Jana Leuenberger, Grischa Ott…·Benoît Zuber

This study improves human iPSC-derived motor neuron synapse formation using optimized differentiation and glutamatergic modulators, resulting in functional and structurally mature neuronal networks.

DOI 10.1101/2025.11.11.687934

humanspatial transcriptomics

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